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A clinical study demonstrated (Tung-Sheng et al., 2011) that a 1:1 mixture of epigallocatechin-3-gallate and Amla (Emblica officinalis) significantly enhanced antioxidant defenses in patients with diabetic nephropathy, synergistically improving clinical outcomes

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Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance

Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine

Contrarily, research suggests that polyphenols can modify the glucocorticoid receptors (GR) activity

Florio, M., Borrell, V